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| Cardiovascular
Medications |
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| Cardiac Glycosides |
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| Depletions |
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| Magnesium |
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Magnesium deficiency affects calcium and vitamin D levels in the body and may
be associated with muscle cramps, irregular heartbeat, high blood pressure,
diabetes, and osteoporosis (bone loss). |

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| Vitamin
B1
(Thiamine) |
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Symptoms of depleted levels of thiamine include weakness, fatigue, anorexia,
constipation, memory loss, confusion, and depression. Deficiency may lead to
beriberi, a condition characterized by inflammation of nerves, heart
irregularities, and fluid retention.
Supporting Research
Cashman K, Flynn A. Optimal nutrition: calcium, magnesium and phosphorus.
Proc Nutr Soc. 1999;58:477-487.
Covington T, ed. Nonprescription Drug Therapy Guiding Patient
Self-Care. St Louis, MO: Facts and Comparisons; 1999:467-545.
Schwinger RH, Erdmann E. Heart failure and electrolyte disturbances.
Methods Find Exp Clin Pharmacol. 1992;14(4):315-325.
Zangen A, Botzer D, Zangen R, Shainberg A. Furosemide and digoxin inhibit
thiamine uptake in cardiac cells. Eur J Pharmacol.
1998;61(1):151-155. |

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| Review Date:
October 2000 |
Reviewed By:
All depletions monographs have been reviewed by a
team of experts including
Derrick M. DeSilva, Jr., MD, Raritan Bay Medical Center, Perth Amboy, NJ;
Jacqueline A. Hart, MD, Department of Internal Medicine, Newton-Wellesley
Hospital, Harvard University and Senior Medical Editor, A.D.A.M., Inc., Boston,
MA; John Hinze, PharmD, NMD, Woodbine, IA; Ruth Marlin, MD, Medical Director and
Director of Medical Education, Preventive Medicine Research Institute,
Sausalito, CA; Brian T Sanderoff, PD, BS in Pharmacy, Clinical Assistant
Professor, University of Maryland School of Pharmacy; President, Your
Prescription for Health, Owings Mills, MD; Leonard Wisneski, MD, FACP, George
Washington University, Rockville, MD; Ira Zunin, MD, MPH, MBA, President and
Chairman, Hawaii State Consortium for Integrative Medicine, Honolulu,
HI.
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The publisher does not accept any responsibility for the
accuracy of the information or the consequences arising from the application,
use, or misuse of any of the information contained herein, including any injury
and/or damage to any person or property as a matter of product liability,
negligence, or otherwise. No warranty, expressed or implied, is made in regard
to the contents of this material. No claims or endorsements are made for any
drugs or compounds currently marketed or in investigative use. This material is
not intended as a guide to self-medication. The reader is advised to discuss the
information provided here with a doctor, pharmacist, nurse, or other authorized
healthcare practitioner and to check product information (including package
inserts) regarding dosage, precautions, warnings, interactions, and
contraindications before administering any drug, herb, or supplement discussed
herein. |
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