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| Antidepressant
Medications |
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| Selective Serotonin Reuptake
Inhibitors
(SSRIs) |
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| Depletions |
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| Melatonin |
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Reduced levels of melatonin in the body have been associated with sleep
disturbances and jet lag. |

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| Protein & Amino
Acids |
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Protein deficiencies are characterized by weakened immune status, including
increased susceptibility to infection, impaired wound healing, muscle and weight
loss, growth retardation, and deterioration in skin and hair
condition. |

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| Editorial Note |
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| Supporting Research |
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|
Avery D, Lenz M, Landis C. Guidelines for prescribing melatonin. Ann
Med. 1998;30:122-130.
Childs PA, Rodin I, Martin NJ, et al. Effect of fluoxetine on melatonin in
patients with seasonal affective disorder and matched controls. Br J
Psychiatry. 1995;166:196-198.
Covington T, ed. Nonprescription Drug Therapy Guiding Patient
Self-Care. St Louis, MO: Facts and Comparisons; 1999:467-545.
Urdaneta E, Idonte I, Larraldo J. Drug-nutrient interactions: inhibition of
amino acid intestinal absorption by fluoxetine. Br J Nutr.
1998;79(5):439-446. |

|
| Review Date:
October 2000 |
Reviewed By:
All depletions monographs have been reviewed by a
team of experts including
Derrick M. DeSilva, Jr., MD, Raritan Bay Medical Center, Perth Amboy, NJ;
Jacqueline A. Hart, MD, Department of Internal Medicine, Newton-Wellesley
Hospital, Harvard University and Senior Medical Editor, A.D.A.M., Inc., Boston,
MA; John Hinze, PharmD, NMD, Woodbine, IA; Ruth Marlin, MD, Medical Director and
Director of Medical Education, Preventive Medicine Research Institute,
Sausalito, CA; Brian T Sanderoff, PD, BS in Pharmacy, Clinical Assistant
Professor, University of Maryland School of Pharmacy; President, Your
Prescription for Health, Owings Mills, MD; Leonard Wisneski, MD, FACP, George
Washington University, Rockville, MD; Ira Zunin, MD, MPH, MBA, President and
Chairman, Hawaii State Consortium for Integrative Medicine, Honolulu,
HI.
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The publisher does not accept any responsibility for the
accuracy of the information or the consequences arising from the application,
use, or misuse of any of the information contained herein, including any injury
and/or damage to any person or property as a matter of product liability,
negligence, or otherwise. No warranty, expressed or implied, is made in regard
to the contents of this material. No claims or endorsements are made for any
drugs or compounds currently marketed or in investigative use. This material is
not intended as a guide to self-medication. The reader is advised to discuss the
information provided here with a doctor, pharmacist, nurse, or other authorized
healthcare practitioner and to check product information (including package
inserts) regarding dosage, precautions, warnings, interactions, and
contraindications before administering any drug, herb, or supplement discussed
herein. |
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